文鑫 副教授
个人简介
文鑫，海南大学副教授，理学博士，博士研究生导师，海南省D类高层次人才。从事南海鱼类遗传与育种的研究工作，研究方向为经济鱼类的人工繁育、基因组选择育种、经济性状的遗传解析。主持国家自然科学青年基金项目1项、国家重点研发项目子课题1项、海南省重点研发项目1项、海南省自然科学青年基金1项、海南大学协同创新中心科研项目1项、海南大学科研启动基金项目1项。先后参与国家重点研发计划项目、国家自然科学基金项目、海南省重大科技计划项目、海南省重点研发计划等课题6项。参与完成石斑鱼人工繁育、石斑鱼雌核生殖育种、石斑鱼多倍体育种、黄颡鱼杂交育种、暗纹东方鲀抗寒育种等多项工作。第一作者或通讯作者发表SCI学术论文13篇，获授权发明专利1项。
学术成果
从事经济鱼类遗传与育种的研究，成果应用于生产并推动相关产业的发展。主要的创新成果如下：
1.聚焦鱼类衍变过程中基因组变化的内在联系，探讨其环境适应性进化的潜在规律，揭示鱼类应对负面环境的调控机制，为创制鱼类优良品种提供基础资料。
2.探索礁栖鱼类的不同体色形成规律，全面解析鳃棘鲈属豹纹鳃棘鲈基因组信息，为开展豹纹鳃棘鲈体色全基因组选育提供基础资料。
3.突破世界濒危物种波纹唇鱼生殖调控和规模化人工繁育技术，获院士专家组鉴定“国际领先成果”；全球首次获得人工雌核生殖石斑鱼优良家系及异源多倍体石斑鱼群体，显著提高育种效率。
目前主要研究方向：
1. 礁栖鱼类体色形成机制及其育种应用
2. 全基因组选择育种技术平台的开发与应用
3. 石斑鱼生殖调控、人工繁育、雌核生殖、多倍体育种技术的研究与应用
代表论文
1.Xin Wen, Peng Chu, Jiejie Xu, Xiaozhen Wei, Dongyong Fu, Tao Wang, Shaowu Yin. Combined effects of low temperature and salinity on the immune response, antioxidant capacity and lipid metabolism in the pufferfish (Takifugu fasciatus) [J]. Aquaculture, 2021, 531: 735866.
2. Yongbo Wang,Xin Wen, Xinhui Zhang, Shuyuan Fu, Jinye Liu, Wei Tan, Ming Luo, Longlong Liu, Hai Huang, Xinxin You, Jian Luo, Fuxiao Chen. Chromosome Genome Assembly of the Leopard Coral Grouper (Plectropomus leopardus) with Nanopore and Hi-C Sequencing Data[J]. Frontiers in genetics, 2020, 11:876.
3.Xin Wen, Yadong Hu, Xinyu Zhang, Xiaozhen Wei, Tao Wang, Shaowu Yin. Integrated application of multi-omics provides insights into cold stress responses in pufferfishTakifugu fasciatus[J]. BMC Genomics, 2019, 20: 563.
4.Xin Wen, Xinyu Zhang, Yadong Hu, Jiejie Xu, Tao Wang, Shaowu Yin. iTRAQ-based quantitative proteomic analysis of Takifugu fasciatus liver in response to low-temperature stress[J]. Journal of Proteomics, 2019, 201: 27-36.
5.Xin Wen, Dan Wang, Xinru Li, Cheng Zhao, Tao Wang, Xiaoming Qian, Shaowu Yin. Differential expression of two Piwil orthologs during embryonic and gonadal development in pufferfish,Takifugu fasciatus[J]. Comparative Biochemistry and Physiology, Part B, 2018, 219-220: 44-51.
6.Xin Wen, Li Wang, Wenxu Zhu, Dan Wang, Xinru Li, Xiaoming Qian, Shaowu Yin. Three toll-like receptors (TLRs) respond toAeromonas hydrophilaor lipopolysaccharide challenge in pufferfish,Takifugu fasciatus[J]. Aquaculture, 2017, 481: 40-47.
7.Xin Wen, Wenshen Li, Jian Luo & Guohua Chen. The complete mitochondrial genome of the Blackspot tuskfish (Choerodon schoenleinii)[J]. Mitochondrial DNA Part A, 2015, 27(4): 2412-2413.
8.Xin Wen, Haizhan Tang, Mengling Zhou, Min Yang, Jie Huang, Junchi Liu, Kexin Zhou, Xin Fan, Weiwei Zhang, Jian Luo. Genome-wide association study of red skin color in leopard coral grouper (Plectropomus leopardus) based on genome resequencing[J]. Aquaculture, 2023, 563: 739014.
9. Jie Huang, Min Yang, Junchi Liu, Haizhan Tang, Xin Fan, Weiwei Zhang,Xin Wen*, Jian Luo. Transcriptome analysis of high mortality phenomena in polyploid fish embryos: An allotriploid embryo case study in hybrid grouper (Epinephelus fuscoguttatus♀×Epinephelus lanceolatus♂)[J]. Aquaculture, 2023, 571: 739446.
10.Xin Wen, Min Yang, Kexin Zhou, Jie Huang, Xin Fan, Weiwei Zhang, Jian Luo. Transcriptomic and proteomic analyses reveal the common and unique pathway (s) underlying different skin colors of leopard coral grouper (Plectropomus leopardus)[J]. Journal of Proteomics, 2022, 266: 104671.
11.Xin Wen, Kaixi Zhang, Dongdong Ouyang, Hengzhen Ye, Jian Luo. Tissue expression of leptin genes inTrachinotus blochiiand responses to fasting and refeeding[J]. Aquaculture Research, 2022, 53(6): 2195-2203.
12. Kexin Zhou, Kaixi Zhang, Xin Fan, Weiwei Zhang, Yesong Liang,Xin Wen*, Jian Luo. The skin-color is associated with its physiological state: A case study on a colorful variety, hybrid grouper (Epinephelus fuscoguttatus×Epinephelus lanceolatus)[J]. Aquaculture, 2022, 549: 737719.
13. Weiwei Zhang, Shuyuan Fu, Xin Fan, Jie Huang, Yesong Liang,Xin Wen*, Jian Luo. Triploid production and performance in hybrid grouper (Epinephelus fuscoguttatus♀×Epinephelus lanceolatus♂)[J]. Aquaculture, 2023, 563: 738891.
发明专利
1. 获授权国家发明专利一项《一种豹纹鳃棘鲈精液低温保存稀释液、保存方法及应用》，专利号ZL202210107918.0；专利权人：海南大学；申请人：文鑫、骆剑、黄杰、樊欣等。
联系方式
电子邮箱 wenxinfish@163.com
