姓　名：尹凯

职　称：高聘副研究员

导师类别：硕士生导师

E-mail：996523@hainanu.edu.cn

一、个人基本情况

尹凯，男，博士，高聘副研究员，硕士生导师,海南大学高层次引进人才

二、教育工作情况

2012.9-2017.6东北农业大学动物医学专业农学学士

2017.9-2020.6东北农业大学临床兽医学专业农学硕士

2020.9-2023.6东北林业大学林学专业农学博士

2023.09-至今 海南大学生命科学学院高聘副研究员

三、科研情况

从事环境污染物对生物体的毒理学机制研究，主要研究微塑料暴露对生物体消化系统毒性及免疫毒性。

四、研究领域

环境污染物的毒理学机制研究。

五、代表性成果

第一作者成果

(1) The antagonistic effect of Se on the Pb-weakening formation of neutrophil extracellular traps in chicken neutrophils. Ecotoxicology and Environmental Safety (2019). IF:7.129，Q1，中科院二区，TOP期刊。

(2) Hydrogen sulfide upregulates miR-16-5p targeting PiK3R1 and RAF1 to inhibit neutrophil extracellular trap formation in chickens. Ecotoxicology and Environmental Safety (2020). IF:7.129，Q1，中科院二区，TOP期刊。

(3) Antagonistic effect of selenium on lead-induced neutrophil apoptosis in chickens via miR-16-5p targeting of PiK3R1 and IGF1R. Chemosphere (2020). IF:8.943，Q1，中科院 二区，TOP期刊。

(4) A comparative review of microplastics and nanoplastics: Toxicity hazards on digestive, reproductive and nervous system. Science of the Total Environment (2021). IF:10.753，Q1，中科院一区，TOP期刊，ESI高被引。

(5) Microplastics pollution and risk assessment in water bodies of two nature reserves in Jilin Province: Correlation analysis with the degree of human activity. Science of the Total Environment (2021). IF:10.753，Q1，中科院一区，TOP期刊。

(6) Polystyrene microplastics up-regulates liver glutamine and glutamate synthesis and promotes autophagy-dependent ferroptosis and apoptosis in the cerebellum through the liver-brain axis. Environmental Pollution (2022). IF:9.988，Q1，中科院二区，TOP期刊，ESI高被引。

(7) Secondary brain injury after polystyrene microplastic-induced intracerebral hemorrhage is associated with inflammation and pyroptosis. Chemico-Biological Interactions (2022). IF:5.168，Q1，中科院二区。

(8) Dose-effect of polystyrene microplastics on digestive toxicity in chickens (Gallus gallus): Multi-omics reveals critical role of gut-liver axis. Journal of Advanced Research (2022). IF:12.822，Q1，中科院二区。

(9) Polystyrene microplastics promote liver inflammation by inducing the formation of macrophages extracellular traps. Journal of Hazardous Materials (2023). IF:14.224，Q1，中科院一区，TOP期刊。