研究方向:

1．功能分子与材料的应用

2．反应动力学和机理研究

3. 功能精细化学品研发

4．生物医学材料和器件应用

讲授课程:

化工原理

电工与电子技术

高等分离工程

Advanced Materials Fabrication Technology

学术兼职:

教育部学位论文评审专家

精细化工青年编委

Smart Molecules 青年编委

Org. Lett. 、Carbohydr. Polym. 、Chem. Eng. J.和Int . J . Biol. Macromol. 等杂志审稿人

学术成就:

周阳，博士，教授，博士生导师。 2017年8月毕业于美国Kent State University并获得博士学位，博士期间师从Nicola E. Brasch 教授和 Paul Sampson教授。从2017年8月至2019年8月在美国University of Michigan师从Mark E. Meyerhoff院士从事博士后研究。留美期间参与3项研究项目，经费共达367万美金。2019年10月以其他类高层次人才引入到海南大学参加工作，主要从事有机合成，药物释放以及生物医疗器械开发与应用。归国后3年内主持国家基金2项，海南省国际合作重点研发1项，海南省面上基金1项，海口市重点研发1项。迄今为止，在相关领域国际期刊杂志Angew. Chem.、Org. Lett.、Green Chem.、Chem. Eng. J.、Carbohydr. Polym.等发表SCI论文50余篇。2022年入选科技部中方青年科学家代表应邀参加第七届金砖国家青年科学家论坛。2023年获得海南大学青年五四奖章。

代表文章：

(1) Zhuang, H.; Shao, J.; Wu, P.; Yu, G.; Fu, K.; Sun, Z.; Cao, M.; Liu, Y.; Zhou, Y. Nitric oxide releasing alginate microspheres for antimicrobial application. Int. J. Biol. Macromol. 2023, 224, 1244-1251.

(2) Zheng, G.; Li, R.; Wu, P.; Zhang, L.; Qin, Y.; Wan, S.; Pei, J.; Yu, P.; Fu, K.; Meyerhoff, M. E.; Liu, Y.; Zhou, Y. Controllable release of nitric oxide from an injectable alginate hydrogel. Int. J. Biol. Macromol. 2023, 252, 126371.

(3) Yang, Z.; Sun, Z.; Liu, Y.; Li, G.; Li, Z.; Liu, C.; Wang, T.; Zhou, Y. Effect of Microencapsulated Long-Chain Chlorinated Paraffin on Flame Retardant of Rigid Polyurethane Foam. ChemNanoMat 2023, 9, e202200473.

(4) Xiong, Z.; Wu, Y.; Zhou, Y.; He, S.; Huang, D.; Zhang, M.; Jiang, Y.; Cheng, L.; Zhao, Z.; Zhao, H.; Lin, H. Rapid determination and health risk assessment of neonicotinoids in source water and tap water of the tropical Hainan Island, China. Environmental Science and Pollution Research 2023.

(5) Wu, P.; Qin, Z.; Dassanayake, R.; Sun, Z.; Cao, M.; Fu, K.; Zhou, Y.; Liu, Y. Antimicrobial MXene-based conductive alginate hydrogels as flexible electronics. Chem. Eng. J. 2023, 455, 140546.

(6) Wu, P.; Cui, Y.; Sun, Z.; Cao, M.; Liu, Y.; Fu, K.; Zhou, Y. Sodium alginate coupled with organosilane quaternary ammonium salt for the antibacterial application. Cellulose 2023, 30, 449-462.

(7) Wen, J.; Liu, Y.; Li, T.; Liu, C.; Wang, T.; Liu, Y.; Zhou, Y.; Li, G.; Sun, Z. Low Cost and Strongly Adsorbed Melamine Formaldehyde Sponge Electrolyte for Nontraditional Quasi-Solid Dye-Sensitized Solar Cells. ACS Applied Energy Materials 2023, 6, 4952-4960.

(8) Tang, L.; Wu, P.; Zhuang, H.; Qin, Z.; Yu, P.; Fu, K.; Qiu, P.; Liu, Y.; Zhou, Y. Nitric oxide releasing polyvinyl alcohol and sodium alginate hydrogels as antibacterial and conductive strain sensors. Int. J. Biol. Macromol. 2023, 241, 124564.

(9) Liu, Y.; Liu, C.; Liu, J.; Qiao, Y.; Liu, Y.; Zhou, Y.; Li, G.; Yang, Z.; Li, Z.; Sun, Z. Dual-response thermosensitive microcapsules based on hydrogel. New J. Chem. 2023, 47, 46-50.

(10) Guo, Q.; Qian, X.; Chen, J.; Wu, Y.; Fu, K.; Sun, Z.; Zheng, Z.; Liu, Y.; Zhou, Y. Synthesis and nitroxyl (HNO) donating properties of benzoxadiazole-based Piloty's acids. Nitric Oxide 2023, 136-137, 24-32.

(11) Zhao, Z.; Lin, Q.; Zhou, Y.; Feng, Y.; Huang, Q.; Wang, X. Pollutant removal from municipal sewage by a microaerobic up-flow oxidation ditch coupled with micro-electrolysis. Royal Society Open Science 2022, 8, 201887.

(12) Zhang, S.; He, F.; Fang, X.; Zhao, X.; Liu, Y.; Yu, G.; Zhou, Y.; Feng, Y.; Li, J. Enhancing soil aggregation and acetamiprid adsorption by ecofriendly polysaccharides hydrogel based on Ca2+- amphiphilic sodium alginate. Journal of Environmental Sciences 2022, 113, 55-63.

(13) Zhang, Q.; Sun, Z.; Guo, Q.; Zhou, Y.; Li, Z.; Wen, J.; Li, F.; Liu, Y.; Jiao, S. Construction of Excellent Visible Light Absorption Heat Storage Slurry Using Phase Change Microcapsules for Solar Thermal Utilization. ChemistrySelect 2022, 7, e202202124.

(14) Wen, J.; Sun, Z.; Qiao, Y.; Zhou, Y.; Liu, Y.; Zhang, Q.; Liu, Y.; Jiao, S. Ti3C2 MXene-Reduced Graphene Oxide Composite Polymer-Based Printable Electrolyte for Quasi-Solid-State Dye-Sensitized Solar Cells. ACS Applied Energy Materials 2022, 5, 3329-3338.

(15) Shao, J.; Zhao, Y.; Li, D.; Xu, S.; Dou, Z.; Sun, Z.; Cao, M.; Fu, K.; Liu, Y.; Zhou, Y. Synthesis and characterization of superhydrophobic fluorinated mesoporous silica for oil/water separation. Microporous Mesoporous Mater. 2022, 112240.

(16) Liu, Y.; Qiao, Y.; Sun, Z.; Zhang, W.; Liu, C.; Wen, J.; Liu, Y.; Zhang, Q.; Zhou, Y.; Chen, J. Visual pressure interactive display of alternating current electroluminescent devices based on hydrogel microcapsules. Journal of Materials Chemistry C 2022, 10, 12221-12231.

(17) Guo, Q.; Wu, Y.; Zhang, L.; Qin, Y.; Bao, J.; Feng, Y.; Liu, Y.; Zhou, Y. Real-time visualization of efficient Nitroxyl (HNO) releasing using fluorescence technique. Sensors and Actuators B: Chemical 2022, 369, 132309.

(18) Zhou, Y.; Wu, P.; Wu, J.; Doverspike, J. C.; Zhang, Q.; Shao, J.; Xi, C.; Liu, Y.; Meyerhoff, M. E. Delivering nitric oxide with poly(n-butyl methacrylate) films doped with S-nitroso-N-acetylpenicillamine. Polymer 2021, 228, 123943.

(19) Yang, S.; Qin, W.; Zhao, X.; He, F.; Gong, H.; Liu, Y.; Feng, Y.; Zhou, Y.; Yu, G.; Li, J. Interfacial self-assembled behavior of pH/light-responsive host-guest alginate-based supra-amphiphiles for controlling emulsifying property. Carbohydr. Polym. 2021, 266, 118121.

(20) Qin, W.; Zhang, S.; Yang, S.; Lin, F.; Zhou, Q.; Gong, H.; Zhao, X.; He, F.; Zhou, Y.; Feng, Y.; Yu, G.; Liu, Y.; Li, J. Highly dispersible magnetic nanoparticles modified by double quaternary ammonium surfactants for efficient harvesting of oleaginous microalgae. Journal of Cleaner Production 2021, 325, 129297.

(21) Liu, S.; Liu, L.; Wang, W.; Zhou, Y.; Dai, G.; Liu, Y. Enhanced Non-Enzymatic Glucose Detection Using a Flower-Like NiCo2O4 Spheres Modified Electrode. J. Anal. Chem. 2021, 76, 993-1001.

(22) Lin, F.; Liu, H.; Zhou, Q.; Zhang, S.; Zhou, Y.; Feng, Y.; Li, J. Amphiphilic alginate-based fluorescent polymer nanoparticles: Fabrication and multifunctional applications. Int. J. Biol. Macromol. 2021, 183, 2152-2161.

(23) Li, Q.; Zhang, L.; Liu, J.; Zhou, J.; Jiao, Y.; Xiao, X.; Zhao, C.; Zhou, Y.; Ye, S.; Jiang, B.; Liu, J. Porous Carbon Nitride Thin Strip: Precise Carbon Doping Regulating Delocalized π-Electron Induces Elevated Photocatalytic Hydrogen Evolution. Small 2021, 17, 2006622.

(24) Li, F.; Sun, Z.; Jiao, S.; Ma, Y.; Zhang, Q.; Zhou, Y.; Wen, J.; Liu, Y. Preparation and Performance of Dual-functional Magnetic Phase-change Microcapsules. Chemistry – An Asian Journal 2021, 16, 102-109.

(25) Li, F.; Jiao, S.; Sun, Z.; Liu, Y.; Zhang, Q.; Wen, J.; Zhou, Y. Self-repairing microcapsules with aqueous solutions as core materials for conductive applications. Green Chemistry 2021, 23, 927-934.

(26) He, F.; Wang, L.; Yang, S.; Qin, W.; Feng, Y.; Liu, Y.; Zhou, Y.; Yu, G.; Li, J. Highly stretchable and tough alginate-based cyclodextrin/Azo-polyacrylamide interpenetrating network hydrogel with self-healing properties. Carbohydr. Polym. 2021, 256, 117595.

(27) Cink, R. B.; Zhou, Y.; Du, L.; Rahman, M. S.; Phillips, D. L.; Simpson, M. C.; Seed, A. J.; Sampson, P.; Brasch, N. E. Mechanistic Insights into Rapid Generation of Nitroxyl from a Photocaged N-Hydroxysulfonamide Incorporating the (6-Hydroxynaphthalen-2-yl)methyl Chromophore. J. Org. Chem. 2021, 86, 8056-8068.

(28) Zhao, Z.; Lin, Q.; Feng, Y.; Zhou, Y.; Wang, X. Determination of monosaccharides hydrolyzed from polysaccharides in activated sludge by ion chromatography–mass spectrometry with online pretreatment of column switching technique. Analytical and Bioanalytical Chemistry 2020, 412, 8061-8071.

(29) Zhao, X.; Fang, X.; Yang, S.; Zhang, S.; Yu, G.; Liu, Y.; Zhou, Y.; Feng, Y.; Li, J. Light-tuning amphiphility of host-guest Alginate-based supramolecular assemblies for photo-responsive Pickering emulsions. Carbohydr. Polym. 2020, 117072.

(30) Zhang, Q.; Murray, G. P.; Hill, J. E.; Harvey, S. L.; Rojas-Pena, A.; Choi, J.; Zhou, Y.; Bartlett, R. H.; Meyerhoff, M. E. Enhanced Hemocompatibility and In Vivo Analytical Accuracy of Intravascular Potentiometric Carbon Dioxide Sensors via Nitric Oxide Release. Anal. Chem. 2020, 92, 13641-13646.

(31) Zhang, B.; Yu, G.; Li, J.; Liu, Y.; Zhou, Y.; Li, Y.; Fang, X.; Jiang, Y. Optimization of extraction technology of poly-mannuronic acid to a green delivery system for the water-insoluble pesticide, λ-Cyhalothrin. Int. J. Biol. Macromol. 2020, 153, 17-25.

(32) Wang, X.; Zhou, Y.; Decker, V.; Meyerhoff, M.; Sun, M.; Cui, Y. Plasticizer-free and pH-independent ion-selective optode films based on a solvatochromic dye. Analytical Methods 2020, 12, 2547-2550.

(33) Liu, S.; Zhou, J.; Zhou, Y.; Liu, Y.; Dai, G. Synthesis and Characterization of a BiNbO4/Bi2S3 Nanocomposite with Improved Visible-Light Photocatalytic Activity. ChemistrySelect 2020, 5, 7170-7176.

(34) Li, Y.; Feng, Y.; Yu, G.; Li, J.; Zhou, Y.; Liu, Y. Preparation and characterization of oil-in-water emulsion based on eco-friendly emulsifiers. Colloids Surf. A Physicochem. Eng. Asp. 2020, 602, 125024.

(35) Jiao, S.; Sun, Z.; Wen, J.; Liu, Y.; Li, F.; Miao, Q.; Wu, W.; Li, L.; Zhou, Y. Development of Rapid Curing SiO2 Aerogel Composite-Based Quasi-Solid-State Dye-Sensitized Solar Cells through Screen-Printing Technology. ACS Applied Materials & Interfaces 2020, 12, 48794-48803.

(36) Jiang, Y.; Yu, G.; Zhou, Y.; Liu, Y.; Feng, Y.; Li, J. Effects of sodium alginate on microstructural and properties of bacterial cellulose nanocrystal stabilized emulsions. Colloids Surf. A Physicochem. Eng. Asp. 2020, 125474.

(37) Fang, X.; Zhao, X.; Yu, G.; Zhang, L.; Feng, Y.; Zhou, Y.; Liu, Y.; Li, J. Effect of molecular weight and pH on the self-assembly microstructural and emulsification of amphiphilic sodium alginate colloid particles. Food Hydrocolloids 2020, 103, 105593.

(38) Cao, M.; Gao, A.; Liu, Y.; Zhou, Y.; Sun, Z.; Li, Y.; He, F.; Li, L.; Mo, L.; Liu, R.; Han, Y.; Yang, Y. Theoretical Study on Electronic Structural Properties of Catalytically Reactive Metalloporphyrin Intermediates. Catalysts 2020, 10, 224.

(39) Zhou, Y.; Tan, J.; Wu, J.; Zhang, Q.; Andre, J.; Xi, C.; Chen, Z.; Meyerhoff, M. E. Nitric oxide releasing poly(vinylidene fluoride-co-hexafluoropropylene) films using a fluorinated nitric oxide donor to greatly decrease chemical leaching. Acta Biomaterialia 2019, 90, 112-121.

(40) Zhou, Y.; Tan, J.; Dai, Y.; Yu, Y.; Zhang, Q.; Meyerhoff, M. E. Synthesis and nitric oxide releasing properties of novel fluoro S-nitrosothiols. Chem. Commun. 2019, 55, 401-404.

(41) Zhou, Y.; Cink, R. B.; Seed, A. J.; Simpson, M. C.; Sampson, P.; Brasch, N. E. Stoichiometric Nitroxyl Photorelease Using the (6-Hydroxy-2-naphthalenyl)methyl Phototrigger. Org. Lett. 2019, 21, 1054-1057.

(42) Zhou, Y.; Bharadwaj, V.; Rahman, M. S.; Sampson, P.; Brasch, N. E.; Seed, A. J. Synthesis and photochemical studies of 2-nitrobenzyl-caged N-hydroxysulfonamides. J. Photochem. Photobiol. A Chem. 2019, 384, 112033.

(43) Sun, Z.; Jiao, S.; Li, F.; Wen, J.; Yu, Y.; Liu, Y.; Cao, M.; Li, L.; Zhou, Y.; She, Y. Acid Activation and Chemical Oxidation in the Synthesis of meso-Tetraphenylporphyrin using a Mixed-Solvent System. Asian J. Org. Chem. 2019, 8, 542-548.

(44) Liu, S.; Liu, Y.; Dai, G.; Bao, X.; Huang, N.; Peng, R.; Zhou, Y. Synthesis and characterization of novel Bi2S3/BiOCl/g-C3N4 composite with efficient visible-light photocatalytic activity. Mater. Lett. 2019, 241, 190-193.

(45) Jiao, S.; Sun, Z.; Zhou, Y.; Li, F.; Wen, J.; Chen, Y.; Du, X.; Li, L.; Liu, Y. Surface-Coated Thermally Expandable Microspheres with a Composite of Polydisperse Graphene Oxide Sheets. Chem Asian J. 2019, 14, 4328-4336.

(46) Doverspike, J. C.; Zhou, Y.; Wu, J.; Tan, X.; Xi, C.; Meyerhoff, M. E. Nitric oxide releasing two-part creams containing S-nitrosoglutathione and zinc oxide for potential topical antimicrobial applications. Nitric Oxide 2019, 90, 1-9.

(47) Zhou, Y.; Zhang, Q.; Wu, J.; Xi, C.; Meyerhoff, M. E. Synthesis and characterization of a fluorinated S-nitrosothiol as the nitric oxide donor for fluoropolymer-based biomedical device applications. J. Mater. Chem. B 2018, 6, 6142-6152.

(48) Zhou, Y.; Cink, R., B.; Fejedelem, Z., A.; Simpson, C., M.; Seed, A., J.; Sampson, P.; Brasch, N., E. Development of Photoactivatable Nitroxyl (HNO) Donors Incorporating the (3-Hydroxy-2-naphthalenyl)methyl Phototrigger. Eur. J. Org. Chem. 2018, 2018, 1745-1755.

(49) Liu, Y.; Gonçalves, A. A. S.; Zhou, Y.; Jaroniec, M. Importance of surface modification of γ-alumina in creating its nanostructured composites with zeolitic imidazolate framework ZIF-67. J. Colloid Interface Sci. 2018, 526, 497-504.

(50) Li, J.; Liu, Y.; Zhou, Y.; Liu, S.; Liang, Y.; Luo, T.; Dai, G. Enhanced visible-light photocatalytic activity of Bi2O2CO3 nanoplates by Fe-doping in the degradation of rhodamine B. Mater. Res. Bull. 2018, 107, 438-445.

(51) Adas, S. K.; Bharadwaj, V.; Zhou, Y.; Zhang, J.; Seed, A. J.; Brasch, N. E.; Sampson, P. Synthesis and HNO Donating Properties of the Piloty's Acid Analogue Trifluoromethanesulphonylhydroxamic Acid: Evidence for Quantitative Release of HNO at Neutral pH Conditions. Chem. Eur. J. 2018, 24, 7330-7334.

(52) Zhou, Y.; Cink, R. B.; Dassanayake, R. S.; Seed, A. J.; Brasch, N. E.; Sampson, P. Rapid Photoactivated Generation of Nitroxyl (HNO) under Neutral pH Conditions. Angew. Chem. Int. Ed. 2016, 55, 13229-13232.

科研项目:

(1) 海南大学科研启动基金，KYQD（ZR）20040, 2020-05 至 2025-05

(2) 中国自然科学基金，青年基金项目，22007025，2021-01 至 2023-12

(3) 中国自然科学基金，地区基金项目，22268018，2023-01至 2026-12

(4) 海南省自然科学基金, 国际合作重点研发， 2023-01至 2024-12

(5) 海口市科学技术工业信息化局基金，海口市科技重点研发， 2023-01至 2024-12

(6) 海南省自然科学基金，面上项目，220MS006，2020-12 至 2023-12

论著专利:

一种自动核磁管清洗仪，202022141720.3

一种氢化亚硝酰供体及其制备方法，202111410694.2

《现代有机合成的反应与新技术研究》， 2021.08

《精细化工概论》，2021.12

合作交流:

目前本课题组分别于与美国密西根大学Mark Meyerhoff教授，美国弗吉尼亚联邦大学Xuewei Wang教授，新西兰奥克兰理工大学Nicola Brasch教授，斯里兰卡斯里贾亚瓦德纳普拉大学Rohan Dassanayake教授分别开展课题合作研究。