陈亚婷女 理学博士

电子邮箱：yatingchen@hainanu.edu.cn

2024年6月以高层次人才引进加入海南大学药学院测试中心

1.教育背景

2020年9月-2024年6月 南开大学化学学院 化学生物学专业 理学博士

2017年9月-2020年6月 温州大学化学与材料工程学院 化学专业 理学硕士

2013年9月-2017年6月 忻州师范学院化学系 化学专业 理学学士

2.科研情况

近五年来共发表SCI论文13篇，SCI收录13篇，入选封面论文2篇，以第一/共一作者发表SCI论文10篇，授权专利一篇。

3.研究领域

代谢标志物氨基酸以及手性小分子的定量分析检测；蛋白质位点特异性修饰及应用；药物分子的有机结构分析及代谢物分析

4.代表性成果

[1]Chen Y. T.; Li B.; Chen J. L. and Su X. C. Stereospecific recognition of a chiral centre over multiple flexible covalent bonds by¹⁹F-NMR.Analyst, 2023, 148, 233-238. IF: 5.227.

[2]Chen Y. T.; Li B.; Chen J. L. and Su X. C. Simultaneous discrimination and quantification of enantiomeric amino acids under physiological conditions by chiral¹⁹F NMR tag.Anal. Chem.2022, 94, 7853-7860. IF: 8.008.

[3]Chen Y. T.;^‡Wang B.;^‡Lei Y. X.; Zhou Y. B.; Guo Y.; Liu M. C.; Gao W. X.; Huang X. B. and Wu H. Y. Stacking-dependent tetracolour luminescence and mechanofluorochromic properties of an isoquinoline derivative with aggregation-induced emission.Mater. Chem. Front.,2022, 6, 459-465. IF: 8.683.

[4] Wang D.;^‡Chen Y. T.;^‡Zhu J. Y.; Lei Y. X.; Zhou Y. B.; Gao W. X.; Liu M. C.; Wu H. Y. and Huang X. B. Construction of mechanofluorochromic and aggregation-induced emission materials based on 4-substituted isoquinoline derivatives.Chem. Asian J.2022, 17, e202200054. IF: 4.839.

[5]Chen Y. T.;^‡Li B.;^‡Li X. Y.; Chen J. L.; Cui C. Y.; Hu K F. and Su X. C. Simultaneous identification and quantification of amino acids in biofluids by reactive¹⁹F-tags.Chem. Commun.2021, 57, 13154-13157. IF: 6.065.

[6]Chen Y. T.; Dai C. H.; Xu X. Y.; Zhou Y. B.; Lei Y. X.; Liu M. C.; Gao W. X.; Huang X. B. and Wu H. Y. Effect of connecting units on aggregation-induced emission and mechanofluorochromic properties of isoquinoline derivatives with malononitrile as the terminal group.J. Phys. Chem. C, 2021, 125, 24180-24188. IF: 4.177.

[7] Feng X.;^‡Chen Y. T.;^‡Lei Y. X.; Zhou Y. B.; Gao W. X.; Liu M. C.; Huang X. B. and Wu H. Y. Multifunctional properties of a star-shaped triphenylamine-benzene-1,3,5-tricarbohydrazide fluorescent molecule containing multiple flexible chains.Chem. Commun., 2020, 56, 13638-13641. IF: 6.065.

[8]Chen Y. T.;^‡Xie Y. F.;^‡Shen H.; Lei Y. X.; Zhou Y. B.; Dai W. B.; Cai Z. X.; Liu M. C.; Huang X. B. and Wu H. Y. Tunable phosphorescence/fluorescence dual emissions of organic isoquinoline-benzophenone doped systems by alkoxy engineering.Chem. Eur. J.2020, 26, 17376-17380. IF: 5.060.

[9]Chen Y. T.; Zhang X. Y.; Wang Z. Q.; Peng J. Q.; Zhou Y. B.; Huang X. B.; Gao W. X.; Liu M. C. and Wu H. Y. Mechanofluorochromism, polymorphism and thermochromism of novel D-π-A piperidin-1-yl-substitued isoquinoline derivatives.J. Mater. Chem. C, 2019, 7, 12580-12587. IF: 8.067.

[10]Chen Y. T.; Zhou Y. B.; Wang Z. Q.; Wang M. Z.; Gao W. X.; Zhou Y. B.; Liu M. C.; Huang X. B. and Wu H. Y. Enhanced mechanofluorochromic properties of 1,4-dihydropyridine-based fluorescence molecules caused by the introduction of halogen atoms.CrystEngComm, 2019, 21, 4258-4266. (Front Cover Paper). IF: 3.117.

[11] Liu M. C.; Xu X. Y.;Chen Y. T.; Ding Q. P.; Lei Y. X.; Wu H. Y. and Huang X. B. Crystal structures, dual-state emissions and polymer-based doped room-temperature phosphorescence of 8-benzyloxyisoquinoline derivatives.CrystEngComm, 2023, 25, 3264-3270. IF: 3.756.

[12] Cui C. Y.; Li B.; Cheng D.; Li X. Y.; Chen J. L.;Chen Y. T.and Su X. C. Simultaneous quantification of biothiols and deciphering diverse GSH stability in different live cells by¹⁹F‑tag.Anal. Chem. 2022, 94, 901-908. IF: 8.008.

[13] Zhou Y. B.;Chen Y. T.; Duan C.; Zeng L. T.; Liu M. C.; Zhou Y. B.; Gao W. X.; Huang X. B. and Wu H. Y. AIE-active 1,4-dihydropyridine-based dual-phase fluorescent sensor with multiple functions.Chem. Asian J.,2019, 14, 2242-2250. (Front Cover Paper). IF: 4.839.

[14] 苏循成，陈亚婷，李斌。一种用于同时鉴定和定量氨基酸的氟探针的制备与应用。授权公告号：CN113943243B.