陈香秀 农学博士 讲师

E-mail: cxiangxiu@hainanu.edu.cn

1.教育背景

2013.09-2017.06 四川农业大学动物医学院，药学，学士

2017.09-2023.06 四川农学大学动物医学院，基础兽医学，博士 （硕博连读）

2.教学情况

（暂无）

3.科研情况

近年来以第一作者（包括并列第一作者）在国际学术期刊如《International Journal of Biological Macromolecules》、《Biomedicine & Pharmacotherapy》、《Frontier in Microbiology》和《International Immunopharmacology》等发表论文7篇。主要参与项目有：四川省科技计划项目“家畜体表皮肤疾病及环境虫媒防控技术示范与应用”和 “抗病营养型新中兽药白藜芦醇干混悬剂的研制”。

4.研究领域

药理与毒理，抗细菌、病毒药物的研发，新药安全性评价。

5.代表性成果

1）Xiangxiu Chen, Junshu Xue, Junjie Zou, Xinghong Zhao, Lixia Li, Renyong Jia, Yuanfeng Zou, Hongping Wan, Yaqin Chen, Xun Zhou, Gang Ye, Lizi Yin, Xiaoxia Liang, Changliang He, Ling Zhao, Huaqiao Tang, Cheng Lv, Xu Song, Zhongqiong Yin^*. Resveratrol alleviated neuroinflammation induced by pseudorabies virus infection through regulating microglial M1/M2 polarization. Biomed Pharmacother. 2023 Jan 31; 160:114271. (TOP, IF=7.419).

2）Xiangxiu Chen, Xu Song, Lixia Li, Yaqin Chen, Renyon Jia, Yuanfeng Zou, Hongping Wan, Ling Zhao, Huaqiao Tang, Cheng Lv, Xinghong Zhao, Zhongqiong Yin*. Resveratrol Inhibits Pseudorabies Virus Replication by Targeting IE180 Protein. Front Microbiol. 2022 Jun 2;13: 891978. (TOP, IF=6.06).

3）Xiangxiu Chen, Xu Song, Xinghong Zhao, Yu Zhang, Yiming Wan, Renyon Jia, Yuanfeng Zou, Lixia Li, Zhongqiong Yin*. “Insights into the Anti-inflammatory and Antiviral Mechanisms of Resveratrol”, Mediators of Inflammation, vol. 2022, 11 pages, 2022. (IF=4.53).

4） Xu Song, Yaqin Chen，Xiangxiu Chen, Xinghong Zhao, Yuanfeng Zou, Lixia Li, Xun Zhou, Mingyue Li, Dongmei, Zhang, Gang Ye, Renyong Jiaand Zhongqiong Yin*. Exosomes from tannic acid-stimulated macrophages accelerate wound healing through miR-221-3p mediated fibroblasts migration by targeting CDKN1b. Int J Biol Macromol. 2023 Jun 2; 244:125088. (TOP, IF=8.025).

5） Wenzhi Tong,Xiangxiu Chen, Xu Song, Yaqin Chen, Renyong Jia, Yuanfeng Zou, Lixia Li, Lizi Yin, Changliang He, Xiaoxia Liang, Gang Ye, Cheng Lv, Junchun Lin, Zhongqiong Yin*. Resveratrol inhibits LPS-induced inflammation through suppressing the signaling cascades of TLR4-NF-κB/MAPKs/IRF3. Exp Ther Med. 2020 Mar;19(3):1824-1834. (IF=2.75).

6）Meng Chen,Xiangxiu Chen, Xu Song, Muhammad Abaidullah, Renyong Jia, Yuanfeng Zou, Lizi Yin, Lixia Li, Changliang He, Gang Ye, Cheng Lv, Zhongqiong Yin*. The immune-adjuvant activity and the mechanism of resveratrol on pseudorabies virus vaccine in a mouse model. Int Immunopharmacol. 2019 Nov; 76:105876. (IF=5.71).

7） Bo Yu,Xiangxiu Chen, Lingling Jiang, Yishun Shang, Xu Song, Sixuan Zhou, Jinge Xu, Jiankang Yu, Qiuting Fu, Shuwei Peng, Songtao Liu, Yue qian Yang, Zhongqiong Yin. Acute and subchronic toxicity and the evaluation of safety pharmacology of Chinese herbal compound preparation “Shikuqin”. Pak J Pharm Sci. 2018 Nov;31(6(Special)):2855-2862. (IF=0.68).