School of Food Science and Engineering Research Key findings Content
December 8, 2023
Research

1.Professors Wentao Xu and Yulan Dong from China Agricultural University were invited to our College for educational and academic exchange and discussion.

17:29 28th Sep, 2023. Yonghuan Yun, Long Wu

On 23rd Sep 2023, our institution had the privilege of hosting Professor Wentao Xu and Professor Yulan Dong from the Faculty of Nutrition and Health at China Agricultural University. They were invited to deliver academic presentations and engage in teaching and research discussions with our faculty and students. During this event, in-depth discussions and exchanges occurred between the visiting professors’ team and our institution’s leadership, including Dean Congfa Li and Secretary Xiucheng Deng.

In the morning, Professor Wentao Xu led an in-depth discussion with students on “Food Safety: A Historical and Dialectical Perspective.” Professor Yulan Dong, on the other hand, emphasized the integration of moral education into curriculum development within the context of the new agricultural sciences. She stressed the importance of aligning curriculum-based moral education with the unique characteristics of college students and their courses, effectively blending ethical elements with in-depth subject knowledge to achieve a subtle yet profound impact. This valuable teaching experience particularly benefited our faculty, especially newly recruited instructors.

2.The Food, Nutrition, and Health Innovation Team has made significant strides in research, including cancer treatment.

11:46, 24th Nov, 2022

The School of Food Science and Engineering is committed to harnessing the unique resources of tropical food. It has established several innovative teams seamlessly integrating into the school's seven major collaborative innovation centers. Since 2022, the researchgroupshavesignificantly contributed to academic research, publishing 57 papers in top-tier journals classified in the JCR-1 Zone.Among these publications, the Food, Nutrition, and Health Innovation Team stands out with 9 high-impact research papers. They have achieved remarkable progress in areas such as cancer treatment and the adaptive evolution mechanisms of bacteria within the human microbiome. Key research achievements include:

In Feb 2022, Professor Xianying Cao and Associate Researcher Ke Jiang from the School of Food Science and Engineering at Hainan University published an academic paper titled “Hierarchical MOF-on-MOF Architecture for pH/GSH-Controlled Drug Delivery and Fe-Based Chemodynamic Therapy” in the international academic journal “Inorganic Chemistry” (JCR-1 Zone, IF 5.44). Notably, this paper has been recognized as a highly cited paper by ESI (Essential Science Indicators). Their research involved successfully constructing a core-shell structured carrier using the MOF-on-MOF strategy. This innovative carrier enabled dual-responsive drug release triggered by changes in pH and glutathione (GSH) levels. The prepared nanocarrier demonstrated excellent chemodynamic/chemotherapeutic synergistic anticancer properties at the cellular level, presenting potential avenues for cancer treatment.

On 5th Apr 2022, the Food, Nutrition, and Health team, led by Associate Professor Yong Yang, collaborated with Professor Qingchun Deng from the Second Affiliated Hospital of Hainan Medical University to achieve a groundbreaking research milestone. Their study featured a natural enzyme, glucose oxidase, as the active component. They harnessed a metal-phenolic network structure as a nanocarrier. Leveraging the physiological characteristic of tumors, which require large amounts of glucose for growth, glucose oxidase was employed to catalyze the conversion of glucose rapidly. This approach effectively cut off the tumor’s nutrient supply, providing a novel avenue for treating drug-resistant tumors. Their research findings were published in the prestigious “Chemical Engineering Journal” (JCR-1 Zone, IF 16.74). The paper is titled “Metal-phenolic networks-encapsulated cascade amplification delivery nanoparticles overcoming cancer drug resistance via combined starvation/chemodynamic/chemotherapy.”

On 29th Oct 29, 2022, a collaboration between Associate Researcher Ke Jiang from the Food, Nutrition, and Health team and Professor Chunxia Li from Shandong University yielded a significant research achievement. They employed a heterogeneous structure strategy to synthesize nano-heterojunctions of Fe3O4 epitaxially grown with MIL-100 and loaded these structures with glucose oxidase. This successful construction resulted in an intelligent Fenton catalyst, offering a fresh perspective for designing cancer treatment platforms. Their research findings were published in “Journal of Materials Science & Technology” (JCR-1 Zone, IF 10.32). The paper is titled “Development of an Intelligent Heterojunction Fenton Catalyst for Chemodynamic/Starvation Synergistic Cancer Therapy.”

Professor Jiachao Zhang from the Innovative Team for the Development and Utilization of Tropical Probiotic Resources, in collaboration with researchers from the University of California, San Diego, has elucidated the adaptive evolution mechanism of bacteria within the human microbiome. Their research paper, titled “Genomic mutations within the host microbiome: Adaptive evolution or purifying selection," was published in the journal "Engineering,” (JCR-1 Zone, IF 12.80).

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