秦天依(博士),海南大学生物医学工程学院副研究员、硕士生导师、海南省拔尖人才。
教育研究经历:
2008-2012:南开大学化学学院,材料化学专业,本科。
2012-2017:中国科学院理化技术研究所,有机化学专业,博士。
2017-2019:深圳大学材料学院,博士后。
2020-2022:华南农业大学植物保护学院,博士后。
2023-至今:海南大学生物医学工程学院朱明强教授团队(分子靶向成像团队)。
研究方向:
1)功能荧光染料及生化应用。
2)荧光探针用于高毒性、致病性有害物的现场检测、生物成像。
3)基于荧光分析法面向慢性疾病标志物的即时检测。
代表论文:
ORCID: 0000-0003-1837-8776
Google scholar: https://scholar.google.com/citations?user=9hYA-KgAAAAJ&hl=zh-CN&oi=ao
(15)Cui-Zhen Lu, Cai-Yun Wang, Chao Song,Tianyi Qin*, Taoyuze Lv, Conghui Zeng, Shihong Chen, Zhongyong Xu, Zhiqing Xun*, Bin Liu*, Ya-Long Wang*, Ming-Qiang Zhu. A ratiometric fluorescent indicator-displacement assay for on-site determination and intracellular imaging of nitroxinil. Food Chemistry, 2024, 435, 137617.
(14)Ze-Jun Li, Cai-Yun Wang, Liang Xu, Zhen-Yu Zhang, Ying-Hao Tang,Tian-Yi Qin *, Ya-Long Wang. A ratiometric fluorescent indicator-displacement assay for on-site determination and intracellular imaging of nitroxinil. Biosensors, 2023, 13(7), 752.
(13)Chao Song, Conghui Zeng,Tianyi Qin *, Taoyuze Lv, Zhongyong Xu, Zhiqing Xun, Lei Wang, Xiaoqiang Chen, Bin Liu *, and Xiaojun Peng. A dual-state-emission chalcone-based supramolecular probe for ratiometric detection of penconazole in environmental samples. Chemical Engineering Journal, 2023, 143610.
Selected publications before HNU
(12) Tianyi Qin, Xiongfei Zhao, Chao Song, Taoyuze Lv, Shihong Chen, Zhiqing Xun, Zhongyong Xu, Zhixiang Zhang, Hanhong Xu, Chen Zhao, Bin Liu*, and Xiaojun Peng. A ratiometric supramolecular fluorescent probe for on-site determination of cyfluthrin in real food samples. Chemical Engineering Journal, 2023, 451, 139022.
(11)Tianhao Jia, Chunmei Pu,Tianyi Qin *, Bin Liu, Guangkai Yao, Zhiqing Xun, Bingfeng Wang, Yongqing Tian, Zhixiang Zhang *, Hanhong Xu *, Chen Zhao *. Azocalixarene-Based Supramolecular System for the Detection of Paraquat via an Improved Indicator Displacement Assay. Journal of Agricultural and Food Chemistry, 2022, 70(50), 15981–15989.
(10)Bin Liu *, Mei Zhou, Yingying Huang, Bing Du, Lei Wang, Zhongyong Xu *,Tianyi Qin *, Xiaojun Peng. Rapid and ratiometric fluorescent detection of phosgene by a red-emissive ESIPT-basedbenzoquinolone probe. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2022, 281, 121619.
(9) Tianyi Qin *, Xiongfei Zhao, Tianhao Jia, Shufan Si, Zhongyong Xu, Bin Liu, Hanhong Xu *, and Chen Zhao *. A surfactant-assisted approach enables the fluorescence tracking of benfluralin in plants. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2022, 280, 121517.
(8) Tianyi Qin, Xiongfei Zhao, Tianhao Jia, Xinfeng Du, Taoyuze Lv, Yongqing Tian, Zhixiang Zhang, Bin Liu *, Hanhong Xu *, and Chen Zhao *. A novel protein-based supramolecular recognition approach for ratiometric fluorescence detection of fipronil. Sensors and Actuators B: Chemical, 2022, 369, 132358.
(7) Tianyi Qin, Xiongfei Zhao, Taoyuze Lv, Guangkai Yao, Zhongyong Xu, Lei Wang, Chen Zhao *, Hanhong Xu *, Bin Liu *, and Xiaojun Peng. General method for pesticide recognition using albumin-based host-guest ensembles. ACS sensors, 2022, 7(7), 2020-2027.
(6)Xiongfei Zhao, Weidong Zheng,Tianyi Qin *, Xinfeng Du, Yanmei Lei, Taoyuze Lv, Mei Zhou, Zhongyong Xu, Lei Wang, Bin Liu *, and Xiaojun Peng. An anti-interference fluorescent probe for point-of-care diagnosis of albuminuria. Sensors and Actuators B: Chemical, 2022, 351, 130980.
(5) Tianyi Qin, Bin Liu *, Zhongyong Xu, Guangkai Yao, Hanhong Xu *, and Chen Zhao *. Flavonol-based small-molecule fluorescent probes. Sensors and Actuators B: Chemical, 2021, 129718.
(4) Tianyi Qin, Bin Liu *, Bing Du, Yingying Huang, Guangkai Yao, Zhiqing Xun, Hanhong Xu *, and Chen Zhao *. Solvatofluorochromic flavonoid dyes with enlarged transition dipole moments enable ratiometric detection of methanol in commercial biodiesel with improved sensitivities. Journal of Materials Chemistry C, 2020, 8(47), 16808-16814.
(3) Tianyi Qin, Yingying Huang, Kangning Zhu, Jiahao Wang, Chengjun Pan, Bin Liu *, and Lei Wang *. A flavonoid-based fluorescent test strip for fast and selective detection of a gaseous nerve agents simulant. Analytica Chimica Acta, 2019,1076,125-130.
(2) Tianyi Qin, Bin Liu *, Yingying Huang, Kuan Yang, Kangning Zhu, Zijie Luo, Chengjun Pan, and Lei Wang *. Ratiometric fluorescent monitoring of methanol in biodiesel by using an ESIPT-based flavonoid probe. Sensors and Actuators B: Chemical, 2018, 277, 484-491.
(1) Tianyi Qin, Bin Liu *, Kangning Zhu, Zijie Luo, Yingying Huang, Chengjun Pan, and Lei Wang *. Organic fluorescent thermometers: Highlights from 2013 to 2017. TrAC-Trends in Analytical Chemistry, 2018, 102, 259-271.
专利:
(5) 刘斌,郑丹娜,秦天依,查尔酮荧光探针及其制备方法与应用、床旁快速检测尿蛋白方法。申请专利号:CN202110705411.0。
(4) 赵晨,秦天依,徐汉虹,一种农药荧光标记成像材料及其制备方法和应用。申请专利号:CN202110461547.1。
(3). 徐汉虹,秦天依,赵晨,一种基于荧光分析的农药检测方法。授权专利号:ZL202110461490.5。
(2). 徐汉虹,秦天依,赵晨,一种基于荧光分析的农药-靶标蛋白筛选方法。授权专利号:ZL202110461531.0。
(1). 刘斌,秦天依,一种用于神经毒气模拟物检测的荧光探针、荧光试纸及其制备方法。授权专利号:ZL201910309692.0。
科研项目:
1.海南省自然科学基金优秀青年基金(224YXQN414),2024.01~2026.12,主持,在研。
2.国家自然科学基金委地区科学基金项目(22364012), 2024.01~2027.12,主持,在研。
3.国家自然科学基金委青年项目(32102243), 2022.01~2024.12,主持,在研。
4.中国博士后基金会, 面上项目(2021M691084), 2022.01~2023.12,主持,结题。
联系方式:qintianyi@hainanu.edu.cn