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      副教授

      郭东波

      2022年05月18日 16:04  点击:

    郭东波(博士) ,副教授,博士生导师,海南省拔尖人才。2018年上海交通大学化学专业毕业,获理学博士学位,师从朱新远教授、张川教授。2018-2020年在华南理工大学从事博士后工作(合作导师:Prof. Song Qing Shi)。2021-2022年在澳门大学以濠江学者(博士后研究员)身份从事科研工作(合作导师:Prof. Zikang Tang, Prof. Songnan Qu)。2022年入职海南大学生物医学工程学院。

    主要研究方向:
    1)碳材料的结构与光学性能的研究;
    2)金属铂创新药设计;
    3)智能微纳水凝胶平台的构建。

    Google scholar: https://scholar.google.com/citations?user=6LHksUQAAAAJ&hl=zh-CN&oi=ao

    学术论文与专利:

    1.Guo D#, Lei J#, Rong D#, Zhang T, Zhang B, Tang Z, Shen H-M*, Deng C-X*, and Qu S*, Photocatalytic Pt(IV)-Coordinated Carbon Dots for Precision Tumor Therapy, Adv. Sci., 2022, 2205106. (IF: 17.521)

    2.Guo D, Huang Y,* Jin X,* Zhang C, Zhu X,* A redox-responsive, in-situ polymerized polyplatinum(IV)-coated gold nanorod as an amplifier of tumor accumulation for enhanced thermo-chemotherapy, Biomaterials, 2021, 266, 120400. (IF: 15.304)

    3.Guo D, Xu S, Yasen W, Zhang C,* Shen J,* Huang Y, Chen D, Zhu X,* Tirapazamine-Embedded Polyplatinum(IV) Complex: A Prodrug Combo for Hypoxia-Activated Synergistic Chemotherapy, Biomater. Sci., 2020, 8, 694-701 (IF: 7.590)

    4.Guo D, Xu S, Huang Y, Jiang H, Yasen W, Wang N, Su Y, Qian J, Li J, Zhang C,* Zhu X, Platinum(IV) complex-based two-in-one polyprodrug for a combinatorial chemo-photodynamic therapy, Biomaterials, 2018, 177, 67-77. (IF: 15.304)

    5.Guo D, Xu S, Wang N, Jiang H, Huang Y, Jin X, Xue B, Zhang C,* Zhu X,* Prodrug-Embedded Angiogenic Vessel-Targeting Nanoparticle: A Positive Feedback Amplifier in Hypoxia-Induced Chemo-Photo Therapy, Biomaterials, 2017, 144, 188-198. (IF: 15.304)

    6.Yuan Y#, Xie B#,Guo D#, Liu C, Jiang G, Lai G, Zhang Y, Hu X, Wu Z, Zheng R, Huang L,* Identification of ALG3 as a Potential Prognostic Biomarker in Lung Adenocarcinoma, Heliyon, 2023, 9, e18065.

    7.Yasen W,* Li B, Aini A, Li Z, Su Y, Zhou L,*Guo D, Qian Q, Chen D, Zhu X, Dong R,* Visible Light-Guided Gene Delivery with Nonviral Supramolecular Block Copolymer Vectors, ACS Appl. Mater. Interfaces, 2023, doi:10.1021/acsami.3c0617 0. (IF: 10.383)

    8.Jiang H,Guo D, Chen D, Wu Y, Jin X,* Zhu X,. A new insight into the reversal of multidrug resistance in cancer by nanodrugs, Biomater. Sci., 2019, 7 (8), 3489-3496. (IF: 7.590)

    9.Huang Y, Shen L,*Guo D, Yasen W, Wu Y, Su Y, Chen D, Qiu F,* Yan D, Zhu X,* A NIR-triggered gatekeeper of supramolecular conjugated unimicelles with two-photon absorption for controlled drug release, Chem. Commun., 2019,55, 6735-6738. (IF:6.065)

    10.Wang N, Jin X,*GuoD, Tong G, Zhu X.* Iron Chelation Nanoparticles with Delayed Saturation as an Effective Therapy for Parkinson Disease, Biomacromolecules, 2017, 18, 461-474. (IF: 6.978)

    11.Jiang H, Chen D,Guo D, Wang N, Su Y, Jin X,* Tong G,* Zhu X., Zwitterionic gold nanorods: low toxicity and high photothermal efficacy for cancer therapy, Biomater. Sci., 2017, 5, 686-697. (IF: 7.590)

    12.Chen D, Jiang H,Guo D, Yasen W, Ao J, Su Y, Pan D, Jin X,* Zhu X,. Anti-biofouling therapeutic nanoparticles with removable shell and highly efficient internalization by cancer cells, Biomater. Sci., 2019, 7, 336-346. (IF: 7.590)

    13.Chen D, Huang Y, Jiang H, Yasen W,Guo D, Su Y, Xue B, Jin X,* Zhu X,. Fabrication of Activity-Reporting Glucose Oxidase Nanocapsules with Oxygen-Independent Fluorescence Variation. ACS Appl. Mater. Interfaces, 2018, 10, 26005-26015. (IF: 10.383)

    14.Huang Y, Qiu F,* Chen D, Shen L, Xu S,Guo D, Su Y, Yan D, * Zhu X,* Color-Convertible, Unimolecular, Micelle-Based, Activatable Fluorescent Probe for Tumor-Specific Detection and Imaging In Vitro and In Vivo, Small, 2017, 13, 1604062. (IF: 15.151)

    15.Yasen W,Dong R, Zhou L, Huang Y,Guo D, Chen D, Li C, Aini A, Zhu X,* Supramolecular block copolymers for gene delivery: Enhancement of transfection efficacy by charge regulation, Chem. Commun., 2017, 53, 12782-12785. (IF: 6.065)

    专利:

    1.四价顺铂类前药与生物还原性药物联用的用途,ZL201810412121.5(授权)

    2.一种乏氧响应性壳聚糖药物载体及其制备方法与应用,ZL201911103912.0(授权)

    3.一种光化疗铂类前药及其制备方法、应用,ZL201710534634.9(授权)

    4.一种壳聚糖载药系统及其制备方法与应用,ZL202010053537.X(授权)

    5.LINC01272在制备肿瘤检测试剂和/或治疗药物中的应用,ZL20201004588.6(授权)

    6.一种含磷阻燃聚芳酯及其制备方法,ZL201210158016.6 (授权)

    主持科研项目:

    1.国家自然科学基金项目(52362006),2024-2027。

    2.国家自然科学基金项目(52203160),2023-2025。

    3.海南大学高层次人才科研启动基金(RZ2200001339),2022-2027。

    4.东莞市社会科技发展(重点)项目(2020507163160),2021-2023。

    5.广东省基础与应用基础研究基金联合基金青年基金项目(2019A1515111055),2020-2022。

    6.博士后科学基金项目,面上项目(一等),2018M640780,2018-2020。

    招生需求:
    招收生物医学工程、化学、材料、生物等相关专业的2-3名硕博研究生、博士后。
    联系方式: dongboguo@hainanu.edu.cn

    海南大学生物医学工程学院
    地址:海南省三亚市崖州区大学路7号 电话:0898-88262314
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