王小俊（博士）海南大学生物医学工程学院研究员（高聘）。2011年本科毕业于华中科技大学生命科学与技术学院，生物科学专业。2011.09-2017.12于武汉光电国家研究中心生物医学光子学功能部攻读博士学位，生物医学光子学专业。博士期间赴美国冷泉港实验室访问合作研究吊灯细胞（Chandelier cell, ChC）GABAergic中间神经元的细胞亚型。2018.07-2020.12华中科技大学光学工程专业博士后，从事全脑神经元单细胞精细结构多色荧光成像方法与神经科学应用研究。2020.12入职海南大学生物医学工程学院。
短期研究方向：
1）单神经元精细解剖结构成像方法和应用研究，发展前沿组织荧光标记、包埋、成像和三维分析技术；
2）模式动物大脑感觉系统的神经元精细解剖、细胞类型（或亚型）、回路连接和功能等。
主持和参与科研项目：
1、 科技创新2030-“脑科学与类脑研究”重大项目，全脑介观神经联接图谱绘制技术平台， 课题4功能分子标记和样本制备技术，2021.12 – 2026.11，主持；
2、 基于表面荧光层析成像的模式动物全脑神经元精细解剖、细胞类型和回路联接研究，海南大学高层次人才科研启动项目，2020.12-2025.12，主持；
3、 中国博士后科学基金特别资助，表面荧光层析成像研究大组织特异类型神经元亚细胞结构( 2019T120661），2019.06 - 2020.11，主持；
4、 中国博士后科学基金面上资助，组织黑化表面层析全脑快速高分辨荧光成像（2018M642826），2018.11 - 2020.11，主持；
5、 科技部973项目，灵长类神经回路精细结构成像的新方法和新工具，课题三：神经回路接点（突触）的光学成像（2015CB755603），2015.01 - 2019-08，参与；
6、 国家自然科学基金面上项目，基于肽型载体稀疏、高亮度标记鼠脑神经元（31470056），2015.01 - 2017.12，参与；
7、 国家自然科学基金面上项目，抑郁发生及恢复过程中小鼠前额叶皮层神经回路可塑性的活体研究（91132726），2015.01 - 2017.12，参与。
近5年学术论文：
1、Xiaojun Wang#, Hanqing Xiong#, Yurong Liu#, Tao Yang#, Anan Li, Fei Huang, Fangfang Yin, Lei Su, Ling Liu, Ning Li, Longhui Li, Shenghua Cheng, Xiaoxiang Liu, Xiaohua Lv, Xiuli Liu, Jun Chu, Tonghui Xu, Fuqiang Xu, Hui Gong, Qingming Luo, Jing Yuan*, Shaoqun Zeng*. Chemical sectioning fluorescence tomography: high-throughput, high-contrast, multicolor, whole-brain imaging at subcellular resolution.Cell Reports. 2021, 34(5), 108709.
2、Xiaojun Wang, Jason Tucciarone, Siqi Jiang, Fangfang Yin, Bor-Shuen Wang, Dingkang Wang, Yao Jia, Xueyan Jia, Yuxin Li, Tao Yang, Zhengchao Xu, Masood A. Akram, Yusu Wang, Shaoqun Zeng, Giorgio A. Ascoli, Partha Mitra, Hui Gong, Qingming Luo*, Z. Josh Huang*. Genetic single neuron anatomy reveals fine granularity of cortical axo-axonic cells.Cell Reports. 2019, 26: 3145-3159.
3、Yadong Gang#, Xiuli Liu#,Xiaojun Wang*, Qi Zhang, Hongfu Zhou,Ruixi Chen, Ling Liu, Yao Jia, Fangfang Yin, Gong Rao, Jiadong Chen, Shaoqun Zeng. Plastic embedding immunolabeled large-volume samples for three-dimensional high-resolution imaging.Biomedical Optics Express. 2017, 8: 3583~3596.
4、Shenghua Cheng,Xiaojun Wang, Yurong Liu, Lei Su, Tingwei Quan, Ning Li, Fangfang Yin, Feng Xiong, Xiaomao Liu, Qingming Luo, Hui Gong*, Shaoqun Zeng*. DeepBouton: automated identification of single-neuron axonal boutons at the brain-wide scale. Frontiers in Neuroinformatics. 2019, 13: 25.
5、Ting Zheng#, Zhao Feng#,Xiaojun Wang, Tao Jiang, Rui Jin, Peilin Zhao, Ting Luo, Hui Gong, Qingming Luo, Jing Yuan*. Review of micro-optical sectioning tomography (MOST): technology and applications for whole-brain optical imaging.Biomedical Optics Express.2019,10: 4075-4096.
6、Qing Huang, Yijun Chen, Shijie Liu, Cheng Xu, Tingting Cao, Yongchao Xu,Xiaojun Wang, Gong Rao, Anan Li, Shaoqun Zeng, Tingwei Quan*. Weakly supervised learning of 3D deep network for neuron reconstruction. Frontiers in Neuroanatomy. 2020, 14:38.
7、Longhui Li, Gong Rao, Xiaohua Lv, Ruixi Chen, Xiaofeng Cheng,Xiaojun Wang, Shaoqun Zeng, Xiuli Liu*. Chemical reactivation of fluorescein isothiocyanate immunofluorescence-labeled resin-embedded samples. Journal of Biomedical Optics. 2018, 23: 1-4.
8、Longhui Li, Ruixi Chen, Xiuli Liu, Ning Li, Xiaoxiang Liu,Xiaojun Wang, Tingwei Quan, Xiaohua Lv, Shaoqun Zeng*. Penetration model for chemical reactivation for resin-embedded green fluorescent protein imaging. Journal of Biomedical Optics. 2018, 24: 1-6.
9、Wenyan Guo, Xiuli Liu, Yurong Liu, Yadong Gang, Xiaobin He, Yao Jia, Fangfang Yin, Pei Li, Fei Huang, Hongfu Zhou, Xiaojun Wang, Hui Gong, Qingming Luo, Fuqiang Xu, Shaoqun Zeng*. Chemical reactivation of resin-embedded pHuji adds red for simultaneous two-color imaging with EGFP. Biomedical Optics Express. 2017, 8: 3281-3288.
10、Hongfu Zhou, Yumiao Xiong, Yu Wang, Xiaojun Wang, Pei Li, Yadong Gang, Xiuli Liu, Shaoqun Zeng*. High-refractive index of acrylate embedding resin clarifies mouse brain tissue.Journal of Biomedical Optics. 2017, 22: 1-4.
11、Qi Zhang, Xiong Yang, Qinglei Hu, Ke Bai, Fangfang Yin, Ning Li, Yadong Gang,Xiaojun Wang, Shaoqun Zeng*. High axial resolution imaging system for large volume tissues using combination of inclined selective plane illumination and mechanical sectioning. Biomedical Optics Express. 2017, 8: 5767~5775.
12、Yadong Gang#, Hongfu Zhou#, Yao Jia, Ling Liu, Xiuli Liu, Gong Rao, Longhui Li,Xiaojun Wang, Xiaohua Lv, Hanqing Xiong, Zhongqin Yang, Qingming Luo, Hui Gong, Shaoqun Zeng*. Embedding and chemical reactivation of green fluorescent protein in the whole mouse brain for optical micro-imaging. Frontiers in Neuroscience.2017, 11:121
13、Tao Yang, Ting Zheng, Zhenhua Shang,Xiaojun Wang, Xiaohua Lv, Jing Yuan, Shaoqun Zeng*. Rapid imaging of large tissues using high-resolution stage-scanning microscopy. Biomedical Optics Express. 2015, 6: 1867~1875.
招生需求：
招收生物学、神经科学、医学、生物医学工程及相关专业的硕士生和博士生；
光学、数学、计算机、电子信息等方向的学生亦欢迎联系（骆清铭团队）。
联系方式：xiwang@hainanu.edu.cn
海大BME