个人简介
职称:教授、硕士生导师
E-mail: liuzhaoqun@hainanu.edu.cn
个人履历
厦门大学学士(2008-2012),中国科学院海洋研究所博士(2012-2017),瑞典乌普萨拉大学访问学者(2019-2020),长期从事海洋动物生理学、分子生态学和功能基因开发利用等领域研究,先后完成了南极磷虾基因组调查和活性肽筛查,阐明了膨大拟蛾螺的精细基因组图谱及其冷泉极端环境适应机制,探究了海洋酸化对贝类早期胚胎发育及成体贝壳形成的抑制作用。近年来以第一/通讯作者发表JCR一区论文17篇,总影响因子>100。申请发明专利5项。
研究方向
目前主要从事珊瑚礁生态系统资源利用方向研究,具体包括:
1. 珊瑚礁生态系统重要功能基因和蛋白的挖掘及利用;
2. 气候变化背景下重要礁栖生物的响应和适应模式;
3. 南海典型造礁石珊瑚环境适应性的分子机制解析。
项目课题
1. 国家自然科学基金面上项目(32072946), 长牡蛎酸化适应跨代遗传的机制研究,主持。
2. 国家自然科学基金青年基金(31802339),去甲肾上腺素调节长牡蛎颗粒细胞合成肿瘤坏死因子的机制研究,主持。
3. 国家重点研发计划项目子课题(2018YFC0310800)深海冷泉生物多样性、环境适应性与应用潜力评估,主持。
4. 国家重点研发计划项目(2018YFD0900500),水产动物疫病发生的分子基础与免疫机制,骨干。
学术奖励
获2017年海洋科学技术一等奖(第4完成人),2017年度中国科学院“优秀博士学位论文”、2017年度中国科学院“院长优秀奖”。海南自贸港E类人才,辽宁省“百千万人才工程”千层次人才。先后承担国家自然科学基金、国家重点研发项目子课题、海南省重点研发国际合作项目等课题,以第一/通讯作者发表SCI论文20篇,担任Frontiers in Physiology客座编委。
论文专著
1.Zhaoqun Liu, Zhi Zhou, Yukun Zhang, Lingling Wang*, Xiaorui Song, Weilin Wang, Yan Zheng, Yanan Zong, Zhao Lv, Linsheng Song*. Ocean acidification inhibits initial shell formation of oyster larvae by suppressing the biosynthesis of serotonin and dopamine. Science of the Total Environment, 2020, 735, 139469.
2.Zhaoqun Liu, Lingling Wang*, Zhao Lv, Zhi Zhou, Weilin Wang, Meijia Li, Qilin Yi, Limei Qiu, Linsheng Song*. The cholinergic and adrenergic autocrine signaling pathway mediates immunomodulation in oyster Crassostrea gigas. Frontiers in Immunology, 2018, 9:284.
3.Zhaoqun Liu†, Zhi Zhou†, Lingling Wang*, Yukun Zhang, Yanan Zong, Yan Zheng, Meijia Li, Weilin Wang, Linsheng Song*. A signaling pathway to mediate the combined immunomodulation of acetylcholine and enkephalin in oyster Crassostrea gigas. Frontiers in Immunology, 2020, 11:616.
4.Zhaoqun Liu, Zhi Zhou, Qiufen Jiang, Lingling Wang*, Limei Qiu, Qilin Yi, Linsheng Song. The neuroendocrine immunomodulatory axis-like pathway mediated by circulating haemocytes in oyster Crassostrea gigas, Open Biology, 2017, 7: 160289.
5.Zhaoqun Liu, Yukun Zhang, Zhi Zhou, Yanan Zong, Yan Zheng, Chang Liu, Ning Kong, Qiang Gao, Lingling Wang*, Linsheng Song*. Metabolomic and transcriptomic profiling reveals the alteration of energy metabolism in oyster larvae during initial shell formation and under experimental ocean acidification. Scientific Reports, 2020, 10:6111.
6. Yuting Huang†, Chao Bian†,Zhaoqun Liu†, Lingling Wang†, Changhu Xue, Hongliang Huang, Yunhai Yi, Xinxin You, Wei Song, Xiangzhao Mao, Linsheng Song*, Qiong Shi*. The First Genome Survey of the Antarctic Krill (Euphausia superba) Provides a Valuable Genetic Resource for Polar Biomedical Research. Marine Drugs, 2020, 18, 185.
7. Yukun Zhang,Zhaoqun Liu*, Yanan Zong, Yan Zheng, Yinan Li, Zirong Han, Lingling Wang*, Linsheng Song. The increased expression of an engrailed gene to sustain shell formation in response to ocean acidification. Frontiers in Physiology, 2020.530435.
8.Zhaoqun Liu, Meijia Li, Qilin Yi, Lingling Wang*, Linsheng Song*. The neuroendocrine-immune regulation in response to environmental stress in marine bivalves. Frontiers in Physiology, 2018, DOI: 10.3389/fphys. 2018. 01080.
9.Zhaoqun Liu, Zhi Zhou, Lingling Wang*, Meijia Li, Weilin Wang, Qilin Yi, Shu Huang, Linsheng Song*. Dopamine and serotonin modulate free amino acids production and Na+/K+pump activity in Chinese mitten crab Eriocheir sinensis under acute salinity stress. Frontiers in Physiology, 2018, DOI: 10.3389/fphys. 2018. 01080.
10.Zhaoqun Liu, Lingling Wang*, Yunchen Yan, Yan Zheng, Wenjing Ge, Meijia Li, Weilin Wang, Xiaorui Song, Linsheng Song. D1 dopamine receptor mediates shell formation in larvae of Pacific oyster Crassostrea gigas under CO2exposure. Developmental and Comparative Immunology, 2018, 84: 337-342.